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GLP-3R RESEARCH GRADE PEPTIDE

# The Triple-Action Peptide That's Changing Metabolic Research

GLP-3R hits THREE different receptors at the same time — something no other peptide can do.

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95% - Client satisfaction rate

- Fat Burning & Energy Research
- Appetite Control Research
- Blood Sugar & Insulin Research

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## Body weight change seen in Phase 2 studies

x

## More receptor targets than single-action peptides

🛒 CHOOSE YOUR PLAN

## Pick Your GLP-3R Research Kit

Lyophilized powder · 10mg vials · ≥99% purity · CoA included · Same-day shipping

⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR VETERINARY USE
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#### Starter Kit

1 Vial · 10mg GLP-3R RUO

$144.00 per vial

- ✓ 1 × GLP-3R 10mg vial
- ✓ Certificate of Analysis
- ✓ Lyophilized powder format
- ✓ ≥99% purity guaranteed

🔥 BEST VALUE
🧬

#### Researcher Bundle

3 Vials Total (Buy 2, Get 1 FREE)

$432 $95.67

- ✓ 3 × GLP-3R 10mg vials
- ✓ 1 vial FREE (valued at $144)
- ✓ Same-day shipping available
- ✓ 30-day satisfaction guarantee

🏭

#### Lab Supply Pack

5 Vials Total (Buy 3, Get 2 FREE)

$720 $86.20

- ✓ 5 × GLP-3R 10mg vials
- ✓ 2 bottles FREE ($288 value)
- ✓ Same-day priority shipping
- ✓ Dedicated research support line

##### 🧾 YOUR ORDER SUMMARY

● Live calculation
GLP-3R 10mg × 3 vials$287
🎉 You Save$145
$95.67 per vial

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## $287

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* For research use only. Not for human or veterinary use.

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## We Stand Behind Every Single Vial We Ship

We've built Pure One Peptides on trust, and we plan to keep it that way. If you're not happy, we're not happy. Just reach out within 30 days and we'll make it right.

## GLP-3R The World First Triple-Receptor Agonist

💚

### Mechanism Analysis

#### Hits the GLP-1 Receptor

This is the same receptor that popular weight-loss drugs target. It helps slow down digestion and reduces hunger signals in the brain.

⭐

### Mechanism Analysis

#### GIP Receptor to Control Fat Storage

It's nearly 9 times more powerful at the GIP receptor than the body's own natural signal. GIP helps control fat storage and how much insulin your body makes.

🔥

### Mechanism Analysis

#### The Secret Metabolic Weapon

This is the secret weapon that no other research peptide has. The glucagon receptor directly tells fat cells to burn up. It's like adding a turbo button to your metabolism research.

⏱️

### Mechanism Analysis

#### Stays Active for About 6 Days

Thanks to a special fatty acid attached to the molecule, GLP-3R stays active for about 6 days. That means you only need to dose once a week.

## The Research Benefits

Based on published study data, here are the areas shown with real breakthroughs.

⚖️

### Body Weight & Fat Loss Research

People using GLP-3R lost up to 24% of their body weight over 48 weeks. That's the biggest number ever seen in a drug study.

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### Blood Sugar & Insulin Research

GLP-3R helps the body manage blood sugar better. It wakes up the cells that make insulin and helps them do their job properly.

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### Fat Burning & Energy Research

Most weight-loss peptides just reduce appetite. GLP-3R does that PLUS it actually tells fat cells to burn up through the glucagon pathway.

❤️

### Heart & Cardiovascular Research

Ongoing research is looking at how GLP-3R affects heart disease risk factors. Researchers can use this to study BP, cholesterol, and inflammation.

🫁

### Liver Fat Research

Fatty liver disease is a huge research area right now. Early data shows GLP-3R can meaningfully reduce liver fat.

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### Receptor Binding Studies

GLP-3R's unique ability to hit three receptors with different strengths makes it a perfect research compound.

💬 RESEARCHER REVIEWS

## What Our Research Customers Are Saying

Real feedback. Verified purchasers. Real Results.

99%+ PURITY
★★★★★

"We've been using PureOne's GLP-3R in our obesity research for months now. The purity is excellent every single time — our HPLC always confirms 99%+."

RAPID DELIVERY
★★★★★

"Ordered on a Tuesday morning and it was at our lab by end of day. The lyophilized powder format is exactly what we need — it's stable, easy to reconstitute, and the concentration is spot on every time. PureOne is our go-to now."

CLEAN CoA
★★★★★

"I was skeptical at first but the consistency between batches has been impressive. Six months of ordering and every CoA shows clean results. Our liver research has moved so much faster thanks to having a reliable triple-agonist compound."

PRODUCT FORMAT

### Lyophilized (Freeze-Dried) Powder

Vials are vacuum-sealed to preserve structural integrity and prevent moisture degradation during transit.

STORAGE -20°C
STABILITY 30 DAYS
FORMAT POWDER
RESEARCH USE ONLY • NOT FOR HUMAN USE
🏆 HOW WE COMPARE

## Pure One Peptides vs. Other GLP-3R Suppliers

Not all research peptide suppliers are the same. Here's why most keep coming back to Pure One Peptides.

What to Look For | ⭐ Pure One Peptides | Generic Supplier
--- | --- | ---
Purity Level | ≥99% Guaranteed | ~95%
Certificate of Analysis (CoA) | ✓ Every order | Sometimes
3rd-Party HPLC Testing | ✓ Independent Lab Verified | ✗ Self-reported
Same-Day Shipping Available | ✓ Order by 2pm ships today | ✗
GMP-Grade Synthesis | ✓ GMP Standards | ✗
Batch-to-Batch Consistency | Highly Consistent | Varies
Customer Support | ✓ Full research support | Limited
30-Day Satisfaction Guarantee | ✓ Full money back | ✗
Ships Within | Same Day | 3–7 days

🧬 GLP-3R FEATURES

## Everything You Get With GLP-3R

Advanced metabolic research support across appetite signaling, insulin sensitivity, lipid pathways, obesity models, and body composition outcomes.

📦 Supplied as Lyophilized (Freeze-Dried) Powder

GLP-3R comes as a stable, freeze-dried powder in a sealed vial — the gold-standard format for research peptides. It stays stable longer, ships safely, and gives you a clean, consistent starting point every time you reconstitute it. No guesswork, no degradation in transit.

💪 Preserves Lean Muscle While Reducing Fat

Unlike most weight-loss compounds that cause muscle loss alongside fat loss, GLP-3R's glucagon pathway selectively targets fat cells for energy. Studies show subjects retain lean body mass — making it a standout compound for body composition research.

🔬 Improved Insulin Sensitivity Research

GLP-3R activates both GLP-1 and GIP incretin pathways, boosting how well cells respond to insulin. Research data shows meaningful improvements in blood sugar control. Perfect for diabetes and metabolic disorder research.

⚡ Appetite Suppression + Energy Burn Together

Most peptides only reduce hunger OR burn fat — not both. GLP-3R does both at once. The GLP-1 receptor cuts appetite; the glucagon receptor tells fat cells to burn energy. Study both mechanisms in one clean protocol.

❤️ Lowers Triglycerides & Bad Cholesterol (LDL)

Published research shows GLP-3R reduces ANGPTL3/8 — the protein responsible for raising triglycerides and LDL cholesterol — via the glucagon receptor pathway. A powerful tool for cardiovascular and lipid metabolism researchers.

🧠 Central Nervous System Appetite Signaling

GLP-1 receptor activation reaches the brain directly, affecting hunger at the brain level — not just in the stomach. GLP-3R opens CNS-metabolic crossover research that single-target peptides simply can't access.

🔄 Synergistic Multi-Pathway Effects

Hitting all three receptors at once creates synergy — the combined effect is stronger than the sum of each pathway individually. Preclinical models confirm GLP-3R outperforms separate compounds given together. One peptide, amplified results.

🩺 Obesity & Type 2 Diabetes Research Models

GLP-3R is among the most studied investigational compounds for obesity and T2D research. It covers both calorie-reduction (appetite) and metabolic acceleration (fat burning + glucose control) in one compound.

📊 THE SCIENCE

## Real Study Data You Can Trust and Reference

GLP-3R isn't a new compound without evidence. It's been studied in one of the biggest clinical trials ever for metabolic research — published in the New England Journal of Medicine.

Clinical validation

### Backed by trial data, body-composition outcomes, and published reference points.

BODY WEIGHT CHANGE IN PHASE 2 STUDY (48 WEEKS)*
GLP-3R 12mg ~24% body weight
-24%
Tirzepatide (dual) ~–22% body weight
-22%
Semaglutide (single) ~–15% body weight
-15%
48wk
Trial Duration
338
Study Participants
NEJM
Published In
2023
Phase 2 Results
01
The Biggest Weight Loss Ever Seen in a Drug Study

The Phase 2 trial showed up to 24% body weight reduction at 48 weeks. That's the largest number ever recorded at that point in any drug study. And they hadn't even hit a plateau yet — the curve was still going down.

02
Almost All the Weight Lost Was Fat, Not Muscle

This is really important. Research shows that most of the weight lost with GLP-3R came from fat mass — not lean muscle. That makes it much more valuable for body composition research than simple calorie restriction.

03
Better Than Using 3 Separate Compounds

Researchers who tried giving animals separate compounds for each receptor found it didn't work as well. The fact that one molecule hits all three at once creates a synergy you just can't replicate by mixing compounds.

NEJM · 2023 PubMed Indexed NCT04881760
❓ QUESTIONS?

## Everything You Want to Know

Our GLP-3R is supplied as a lyophilized (freeze-dried) powder in sealed vials — this format keeps the peptide stable and protected during shipping and storage. When it arrives, store the dry powder in a cool, dry, dark place. For longer storage, keep it at -20°C. Once you reconstitute it with bacteriostatic water or appropriate buffer, keep it in the fridge at 2–8°C and use it within 28–30 days. Avoid repeated freeze-thaw cycles to preserve compound integrity.
GLP-1S only activates one receptor (GLP-1). That's good, but it's like a one-trick pony. GLP-3R activates three receptors at once — GLP-1, GIP, and glucagon. The glucagon part is what really sets it apart, because it directly tells fat cells to burn up, which GLP-1S can't do at all.
The CoA is a document that proves the quality of what you're getting. It includes: the exact purity percentage from HPLC testing, mass spectrometry confirmation of the right molecule, batch number, date it was made, how to store it, and the molecular weight and formula. You can use it in your research documentation.
Every batch is made to ≥99% chemical purity. We verify this using HPLC (a machine that separates and measures each chemical) and Mass Spectrometry (which confirms the exact molecule). A Certificate of Analysis comes with every order so you can see the numbers yourself. We also encourage you to run your own test.
Lyophilized (freeze-dried) powder is the gold standard format for research peptides. Removing the water from the compound during manufacturing makes it much more stable — it can be stored at room temperature short-term or at -20°C long-term without degrading. This format also makes shipping easier and safer. When you're ready to use it in your research, simply reconstitute with sterile bacteriostatic water or an appropriate buffer solution. The result is a consistent, clean, measurable concentration every time — which is critical for reproducible research results.
Easy — just contact us within 30 days. If the product doesn't match the CoA, fails your own purity test, or arrives damaged, we'll send a replacement or give you a full refund. No questions asked. We want every researcher to be completely confident ordering from us.
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